Lysate” comes from the Latin word lysis, which translates as “to break open.” So Platelet Lysate is made up of platelets that have been broken open in some way. Platelets contain alpha granules, which are small packets where their growth factors live. When you break open a platelet, the growth factors are released all at once rather than being released over a longer term. As a result, you can benefit from a higher dose of growth factors, in a shorter period of time, with a platelet lysate (PL) than if you used platelet-rich plasma (PRP). Similar to an immediate release pill, which releases a drug more quickly than a sustained release pill that releases a drug over a longer timeframe.